Catalog Number - 68508-05P

Cogent RP C8™ HPLC Columns are designed for reliable reversed-phase separations using a traditional octyl (C8) bonded stationary phase. The phase is produced using ultra-high purity silica with an eight-carbon ligand and is fully double end capped to reduce secondary interactions and improve peak shape. As a USP L7 equivalent chemistry, RP C8™ columns are widely used for hydrophobic and moderately non-polar analytes and can serve as a suitable alternative in many methods developed for similar C8 phases.

68508-05P is packed with 5 µm RP C8™ particles featuring a 100 Å pore size in a 4.6 mm ID x 50 mm length format. The short 50 mm column length is ideal for fast analyses, rapid screening studies, and method development applications where reduced run times are desired. The 5 µm particle size provides low backpressure while maintaining dependable chromatographic performance on conventional HPLC systems. This column is particularly useful for hydrophobic compounds, neutral molecules, and long-chain fatty acids where somewhat lower retention than a comparable C18 column is preferred.

This column is frequently selected as a scouting column during analytical method development and preparative method optimization. The shorter column format allows rapid evaluation of selectivity, retention, and mobile phase conditions before scaling separations to larger column formats for purification or production workflows.

Key Benefits

• RP C8™ stationary phase

• USP L7 equivalent chemistry

• Octyl (C8) bonded phase

• Fully double end capped

• Ultra-high purity silica support

• 100 Å pore size

• Fast 50 mm column length

• Lower retention than C18 phases

• Low backpressure with 5 µm particles

• Ideal for scouting and method development

Typical Applications

• Reversed-phase HPLC

• Method development

• Method scouting

• Long-chain fatty acid analysis

• Hydrophobic compound separations

• Neutral compound analysis

• Pharmaceutical analysis

• Environmental testing

• Food and beverage analysis

• Preparative method evaluation

Specifications

• Product Type: HPLC Column

• Stationary Phase: RP C8™

• USP Classification: L7

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double End Capped

• Particle Size: 5 µm

• Pore Size: 100 Å

• Column Dimensions: 4.6 mm ID x 50 mm

• Recommended Flow Rate: 1.0–2.0 mL/min

• Column Hardware: Stainless Steel

• Brand: Cogent

Important Notes

• Designed for fast reversed-phase HPLC analyses

• Provides lower retention than comparable C18 columns

• Suitable for hydrophobic and moderately non-polar compounds

• Excellent choice for long-chain fatty acid separations

• Commonly used as a scouting column during method development

• 50 mm length helps reduce analysis times and solvent consumption

• 5 µm particles provide low backpressure and broad instrument compatibility

• Compatible with standard HPLC systems operating at conventional flow rates

• Manufactured using ultra-high purity silica and fully double end capped bonding technology